Aripiprazole alone or in combination for acute mania

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Aripiprazole alone or in combination for acute mania.

BACKGROUND Bipolar disorder is a mental disorder characterised by episodes of elevated or irritable mood (manic or hypomanic episodes) and episodes of low mood and loss of energy (depressive episodes). Drug treatment is the first-line treatment for acute mania with the initial aim of rapid control of agitation, aggression and dangerous behaviour. Aripiprazole, an atypical antipsychotic, is used...

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Aripiprazole monotherapy in acute mania : 12 - week randomised

Bipolar disorder is a lifelong episodic illness requiring long-term treatment, yet there remains a need for well-tolerated and clinically effective maintenance of effect and continuation therapies. Aripiprazole has a novel pharmacological profile; partial agonism at dopamine D 2 and D 3 and serotonin 5-HT 1A receptors, and antagonism at 5-HT 2A receptors. 1–5 Aripiprazole has been shown to impr...

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Misoprostol Alone or in Combination with Methotrexate for Termination of Pregnancy at First Trimester

Abortion is an important problem in obstetrics throughout the world. The common and standard method for pregnancy termination at first trimester is surgery (curettage). Nowadays, an effective method of pregnancy termination at first trimester is medical treatments. The aim of this study is to compare misoprostol alone or in combination with methotrexate for pregnancy termination at first trimes...

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Misoprostol Alone or in Combination with Methotrexate for Termination of Pregnancy at First Trimester

Abortion is an important problem in obstetrics throughout the world. The common and standard method for pregnancy termination at first trimester is surgery (curettage). Nowadays, an effective method of pregnancy termination at first trimester is medical treatments. The aim of this study is to compare misoprostol alone or in combination with methotrexate for pregnancy termination at first trimes...

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[Advances in the treatment of mania: aripiprazole].

Aripiprazole is a dopamine partial agonist antipsychotic drug that has just been approved in Europe for its use in the treatment of acute mania and for the prevention of manic episodes in bipolar disorder. Its efficacy in mania is superior to that of placebo, both as monotherapy and as adjunctive therapy, and comparable to that of haloperidol and lithium. From the safety perspective it is remar...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2013

ISSN: 1465-1858

DOI: 10.1002/14651858.cd005000.pub2